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Radical Cystectomy (Bladder Cancer)

Removal of the entire bladder and urinary diversion in muscle-invasive bladder cancer.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Radical Cystectomy (Bladder Cancer)?

Radical cystectomy in muscle-invasive bladder cancer (≥T2) is the removal of the entire bladder, adjacent organs (prostate and seminal vesicles in men; uterus and anterior vaginal wall in women) and an extended pelvic lymph node dissection.

Urinary diversion options are: ileal conduit (Bricker — drainage to an external bag via stoma), orthotopic neobladder (a new bladder fashioned from small bowel with voiding through the urethra) and continent cutaneous diversion (Indiana pouch).

Neoadjuvant cisplatin-based chemotherapy (3–4 cycles) is the standard approach and has been shown to improve survival. Robotic cystectomy is becoming more common.

Symptoms

Muscle-invasive bladder cancer (≥T2)
High-risk NMIBC unresponsive to BCG
Recurrent high-grade bladder cancer
Carcinoma in situ (CIS) with BCG failure
Diffuse superficial bladder cancer

Risk Factors

High perioperative complication rate (30–60%)
Ileus (delayed return of bowel function)
Urinary infection and pyelonephritis
Metabolic acidosis (due to use of bowel segment)
Erectile dysfunction and incontinence

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When a diagnosis of muscle-invasive bladder cancer is made — multidisciplinary evaluation
  • If postoperative fever, ileus or signs of urinary leak develop
  • For problems with stoma care or neobladder catheterisation
  • For long-term renal-function and metabolic follow-up

Treatment Methods

01
Neoadjuvant cisplatin-based chemotherapy (gemcitabine + cisplatin)
02
Robotic or open radical cystectomy with extended pelvic lymphadenectomy (ePLND)
03
Orthotopic neobladder reconstruction (in suitable patients)
04
Ileal conduit (Bricker) diversion
05
Immunotherapy (neoadjuvant or adjuvant, in selected cases)

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.