The information on this website is not intended for diagnosis or treatment. Please consult your physician for health concerns.

+90 850 321 50 00

Intraprostatic Botulinum Toxin Injection

Botox treatment for prostate enlargement.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Intraprostatic Botulinum Toxin Injection?

Intraprostatic botulinum toxin injection is a treatment option for patients with lower urinary tract symptoms due to benign prostatic hyperplasia (BPH) who are unsuitable for surgery or unresponsive to medical therapy.

Botulinum toxin A (BTA) acts by relaxing prostatic smooth muscle and inducing apoptosis in prostatic gland tissue. It is injected into prostate lobes under transrectal ultrasonography or cystoscopy guidance. Generally 100-300 units are used.

The effect begins within 2-4 weeks and may last 6-12 months. Repeat injections may be needed. It is a good alternative for patients with high anesthesia risk, those on anticoagulants, and those who refuse surgery.

Symptoms

Difficulty in urination (BPH symptoms)
Frequent urination (pollakiuria)
Nighttime urination (nocturia)
Weak urinary stream
Urinary retention (chronic catheterized patients)

Risk Factors

Transient hematuria
Urinary infection (2-3%)
Inadequate response (in some patients)
Transient dysuria
Diminishing effect over time (need for repeat injection)

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If adequate response is not obtained from BPH medical therapy
  • When surgical risks are high (advanced age, comorbidities)
  • If anticoagulant therapy cannot be discontinued
  • If the patient does not prefer surgery

Treatment Methods

01
Transrectal US-guided intraprostatic BTA injection
02
Cystoscopy-guided injection (alternative method)
03
Alpha-blocker and 5-alpha reductase inhibitor combination (medical)
04
TUR-P or HoLEP (definitive surgery, if eligible)
05
Prostate artery embolization (PAE, other minimally invasive option)

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Üroloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

Book AppointmentContact Us

Related Health Topics

Other articles from the same department you may want to explore.

ESWL (Extracorporeal Shock Wave Lithotripsy)

Üroloji

ESWL delivers focused extracorporeal shock waves to fragment kidney stones into small pieces that can pass through the urinary tract spontaneously.

TURP (Transurethral Resection of the Prostate)

Üroloji

TURP is the endoscopic resection of prostatic adenoma causing lower urinary tract obstruction in benign prostatic hyperplasia.

Cystoscopy (Bladder Endoscopy)

Üroloji

Cystoscopy passes a thin endoscope through the urethra to inspect the bladder and urethra directly for both diagnostic and therapeutic purposes.

Varicocelectomy (Varicocele Surgery)

Üroloji

Varicocelectomy is a microsurgical or laparoscopic ligation of the enlarged veins of the pampiniform plexus; it plays an important role in treating male infertility.

Nephrectomy (Kidney Cancer Surgery)

Üroloji

Nephrectomy is the surgical procedure to remove a kidney with cancer (renal cell carcinoma) either radically or partially.

Radical Prostatectomy

Üroloji

Radical prostatectomy is the surgical removal of the entire prostate and seminal vesicles in localised prostate cancer; the robotic approach is today's standard.

Urethroplasty (Urethral Stricture Surgery)

Üroloji

Urethroplasty is the surgical widening or reconstruction of a urethral stricture; success rates are 85-95%.

Radical Orchiectomy (Testicular Cancer)

Üroloji

Radical inguinal orchiectomy is the surgery to remove the cancer-bearing testis along with the spermatic cord through a groin incision, used both for diagnosis and treatment of testicular cancer.

Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.