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Wide Resection with Tumor Megaprosthesis

Limb-salvage surgery with modular tumor megaprostheses after wide resection of bone sarcomas.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Ortopedi ve Travmatoloji department. Book Appointment →

What is Wide Resection with Tumor Megaprosthesis?

Wide resection with tumor megaprosthesis is a limb-salvage strategy used after oncologic wide excision of primary bone sarcomas (osteosarcoma, Ewing sarcoma, chondrosarcoma) or metastatic bone disease around the proximal femur, distal femur, proximal tibia, proximal humerus and pelvis.

Modular tumor endoprostheses allow tailored reconstruction after segmental resection with anatomic restoration of joint function, soft-tissue reattachment via Trevira tubes or biologic augmentation, and options for expandable implants in growing children.

Surgery is part of a multidisciplinary oncology pathway including neoadjuvant chemotherapy, advanced imaging, image-guided resection planning, perioperative infection prophylaxis and structured rehabilitation, with reported limb survival exceeding 80% at 5-10 years.

Symptoms

Persistent bone pain at rest
Pathologic fracture
Palpable mass in extremity
Functional limitation of adjacent joint
Progressive radiographic lytic or sclerotic lesion
Symptoms of metastatic bone disease
Constitutional symptoms in primary sarcoma

Risk Factors

Primary bone sarcoma diagnosis
Metastatic carcinoma to bone
Adjacent joint or neurovascular involvement
Pathologic fracture
Prior radiation therapy
Failed limb-salvage with conventional reconstruction
Recurrent disease after prior surgery

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • New persistent bone pain in adolescent or adult
  • Pathologic fracture without trauma
  • Known sarcoma needing surgical planning
  • Symptomatic bone metastasis
  • Aseptic loosening of prior tumor implant
  • Periprosthetic infection
  • Need for revision after wear, fracture or oncologic relapse

Treatment Methods

01
Multidisciplinary oncology evaluation and biopsy
02
Neoadjuvant chemotherapy or radiation as indicated
03
Wide oncologic resection with negative margins
04
Modular tumor megaprosthesis reconstruction
05
Soft-tissue reconstruction (Trevira tube, mesh or biologic)
06
Expandable prosthesis in growing children
07
Structured rehabilitation and long-term oncologic surveillance

Which Department to Visit?

You can visit our Ortopedi ve Travmatoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Ortopedi ve Travmatoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.