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Megaprosthesis Tumor Reconstruction

Modular endoprostheses for limb salvage after wide resection of bone tumors.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Ortopedi ve Travmatoloji department. Book Appointment →

What is Megaprosthesis Tumor Reconstruction?

Megaprostheses are large modular metallic endoprostheses used to reconstruct skeletal defects after wide resection of primary or metastatic bone tumors involving the proximal and distal femur, proximal tibia, proximal humerus, and pelvis.

Modern designs offer modular components, hydroxyapatite collars to reduce stress shielding, silver-coated surfaces to reduce infection, and rotating-hinge knee mechanisms; expandable prostheses are available for skeletally immature children.

Outcomes depend on tumor biology, surgical margins, soft tissue reconstruction, infection prevention, and rehabilitation; long-term complications include aseptic loosening, infection, and mechanical failure requiring revision.

Symptoms

Bone pain at tumor site
Palpable mass and swelling
Pathologic fracture
Limited joint range of motion
Limp and functional impairment
Weight loss and systemic symptoms in advanced disease
Local recurrence at prior surgical site

Risk Factors

Osteosarcoma in adolescents and young adults
Ewing sarcoma
Chondrosarcoma
Metastatic bone disease
Failed prior limb salvage surgery
Massive bone defect after revision arthroplasty
Trauma with extensive bone loss

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Suspected primary bone tumor
  • Pathologic fracture in known cancer patient
  • Massive bone defect after tumor resection
  • Failed limb salvage requiring revision
  • Severe functional disability after tumor surgery
  • Suspected local recurrence
  • Need for complex limb reconstruction

Treatment Methods

01
Multidisciplinary tumor board planning
02
Neoadjuvant chemotherapy and imaging staging
03
Wide resection with negative margins
04
Megaprosthesis reconstruction with appropriate soft tissue coverage
05
Adjuvant chemotherapy or radiotherapy when indicated
06
Long-term oncologic and orthopedic surveillance
07
Rehabilitation and functional optimization

Which Department to Visit?

You can visit our Ortopedi ve Travmatoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Ortopedi ve Travmatoloji Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.