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Male Infertility and Micro-TESE

In non-obstructive azoospermia, sperm can be retrieved from the testis with microsurgery and pregnancy can be achieved with IVF/ICSI.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kadın Hastalıkları ve Doğum department. Book Appointment →

What is Male Infertility and Micro-TESE?

Azoospermia is the absence of sperm in the ejaculate and represents an advanced form of male infertility. It is divided into obstructive (normal spermatogenesis but obstructed ducts) and non-obstructive (impaired spermatogenesis) types. Micro-TESE is currently the gold-standard approach in non-obstructive azoospermia.

Micro-TESE is the procedure of examining testicular tubules one by one under an operating microscope and obtaining samples from areas with spermatogenesis. Compared to conventional TESE, less tissue is consumed, sperm retrieval rates are higher (40-60%), and damage to the testis is minimized.

The retrieved sperm are injected into eggs by ICSI to form embryos. Success rates depend on the underlying etiology (Klinefelter syndrome, Y chromosome microdeletion, cryptorchidism, post-chemotherapy). Preoperative hormonal optimization may improve treatment success.

Symptoms

Consecutive azoospermia on two semen analyses
Small, hypotrophic testes
Lack of secondary sex characteristics
Reduced erection and libido (in some cases)
Findings of Klinefelter syndrome
History of cryptorchidism
Couple presenting with infertility

Risk Factors

Klinefelter syndrome (47,XXY)
Y chromosome microdeletions
Cryptorchidism
History of radiotherapy or chemotherapy
Varicocele
Testicular trauma or infection

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When infertility lasts more than one year
  • For further evaluation when azoospermia is detected
  • In the presence of Klinefelter or Y chromosome deletion
  • Pre- or post-chemotherapy evaluation
  • When varicocele coexists with infertility

Treatment Methods

01
Hormonal profile (FSH, LH, testosterone, prolactin, estradiol)
02
Karyotype and Y chromosome microdeletion analysis
03
Repair of varicocele if present
04
Micro-TESE surgery (under operating microscope)
05
ICSI and embryo transfer with retrieved sperm
06
Preoperative hormonal optimization with HCG/FSH

Which Department to Visit?

You can visit our Kadın Hastalıkları ve Doğum department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kadın Hastalıkları ve Doğum Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.