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Inflammatory Bowel Disease (IBD) in Pregnancy

Pre-conception remission in patients with Crohn's and ulcerative colitis ensures optimal maternal-fetal outcomes.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kadın Hastalıkları ve Doğum department. Book Appointment →

What is Inflammatory Bowel Disease (IBD) in Pregnancy?

Crohn's disease and ulcerative colitis are chronic immune-mediated diseases that can affect both maternal health and fetal outcomes during pregnancy. Achieving preconception remission is the basic goal for low disease flare and healthy pregnancy outcomes.

Most drugs used in treatment (5-ASA, azathioprine, anti-TNF biologics) can be continued during pregnancy, while methotrexate and some immunomodulators are contraindicated. Anti-TNF therapy may require dose adjustment in late third trimester.

IBD monitoring is performed with fecal calprotectin, CRP, hemoglobin, albumin, B12, and vitamin D levels. When endoscopic evaluation is needed, flexible sigmoidoscopy can be performed safely.

Symptoms

Bloody diarrhea and abdominal pain
Weight loss
Increased fatigue
Anemia and hypoalbuminemia
Flare of perianal disease
Extraintestinal symptoms (arthritis, uveitis)

Risk Factors

Active disease before pregnancy
Treatment compliance issues
Severe perianal disease
History of previous preterm birth
Short bowel syndrome
Iron and B12 deficiency

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • For preconception evaluation
  • When flare symptoms begin
  • Increased weight loss and fatigue
  • In conditions requiring drug change

Treatment Methods

01
Preconception remission strategy
02
Joint follow-up of gastroenterology and MFM
03
Continuation of appropriate biological therapy
04
Fecal calprotectin and CRP monitoring
05
Nutritional support and micronutrient replacement
06
Anti-TNF dose planning and postpartum reassessment

Which Department to Visit?

You can visit our Kadın Hastalıkları ve Doğum department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kadın Hastalıkları ve Doğum Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.