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Endometrial Cancer

The most common gynecological cancer in postmenopausal women.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kadın Hastalıkları ve Doğum department. Book Appointment →

What is Endometrial Cancer?

Endometrial cancer is a gynecological cancer that originates from the endometrial epithelium and is most commonly seen in postmenopausal women aged 55-70. It is classified into two main groups: type 1 (endometrioid, estrogen-dependent) and type 2 (serous, clear cell, more aggressive).

Chronic estrogen exposure, obesity, metabolic syndrome, nulliparity, late menopause, tamoxifen use, and Lynch syndrome are the main risk factors. The diagnostic finding is abnormal uterine bleeding.

Diagnosis uses transvaginal ultrasound, endometrial biopsy, and hysteroscopy. Treatment is total hysterectomy with bilateral salpingo-oophorectomy ± lymph node assessment. In advanced stages, adjuvant radiotherapy, chemotherapy, and hormone therapy are added.

Symptoms

Postmenopausal vaginal bleeding
Abnormal bleeding in the perimenopausal period
Foul-smelling discharge
Pelvic pain and pressure
Abdominal distension in advanced stages
Weight loss and fatigue

Risk Factors

Obesity and diabetes
Unopposed estrogen use
Late menopause and nulliparity
Tamoxifen
PCOS history
Lynch syndrome

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Any postmenopausal bleeding
  • Perimenopausal abnormal uterine bleeding
  • When discharge and pelvic pressure are added
  • For screening in those with a family history
  • At post-treatment follow-up exams

Treatment Methods

01
Transvaginal ultrasound and endometrial biopsy
02
Histopathological diagnosis with hysteroscopy
03
FIGO staging
04
Total hysterectomy + bilateral salpingo-oophorectomy
05
Adjuvant radiotherapy/chemotherapy according to stage
06
Hormonal therapy and follow-up protocols

Which Department to Visit?

You can visit our Kadın Hastalıkları ve Doğum department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kadın Hastalıkları ve Doğum Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.