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Eclampsia

A life-threatening hypertensive emergency in pregnancy presenting with seizures.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kadın Hastalıkları ve Doğum department. Book Appointment →

What is Eclampsia?

Eclampsia is the occurrence of tonic-clonic seizures, otherwise unexplained, in a pregnant woman with preeclampsia. Seizures may occur antepartum, intrapartum, or postpartum, and develop on the basis of cerebral vasospasm, endothelial dysfunction, and edema.

The pathophysiology involves placental ischemia, impaired angiogenesis (sFlt-1/PlGF imbalance), oxidative stress, and a systemic inflammatory response. Brain imaging often demonstrates findings of posterior reversible encephalopathy syndrome (PRES).

The treatment approach simultaneously addresses airway protection, seizure control (magnesium sulfate is first-line), blood pressure management, and termination of pregnancy after the 34th week. Even at earlier gestational ages, delivery is decided once maternal stabilization is achieved.

Symptoms

Sudden onset of tonic-clonic seizure
Severe headache and visual disturbances
Epigastric or right upper quadrant pain
Confusion and agitation
Sudden rise in blood pressure
Postictal confusion after seizure

Risk Factors

History of severe preeclampsia
First pregnancy and advanced maternal age
Chronic hypertension and renal disease
Multiple pregnancy
Diabetes and obesity
Antiphospholipid syndrome and autoimmune diseases

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Emergency presentation when seizure or loss of consciousness develops in pregnancy
  • When severe headache and sudden visual disturbances occur
  • When right upper quadrant pain and nausea are added
  • Sudden deterioration in a pregnant woman with preeclampsia diagnosis
  • New-onset seizures within the first six weeks postpartum

Treatment Methods

01
Airway protection and lateral recumbent positioning
02
Magnesium sulfate loading and maintenance infusion
03
Hypertension control (labetalol, hydralazine, nifedipine)
04
Continuous maternal-fetal monitoring
05
Planned delivery (often cesarean) after stabilization
06
Postpartum intensive care monitoring for 24-48 hours

Which Department to Visit?

You can visit our Kadın Hastalıkları ve Doğum department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kadın Hastalıkları ve Doğum Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.