Adenomyosis

A painful gynaecologic disease in which endometrial tissue invades the uterine wall.

Written by: Saygı Hospital Health Guide Editorial Board

Last updated: June 9, 2026

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kadın Hastalıkları ve Doğum department. Book Appointment →

What is Adenomyosis?

In adenomyosis the endometrial glands and stroma penetrate the myometrium where they undergo cyclical bleeding and inflammation. The uterus enlarges, becomes firm and adopts a globular contour.

It is most often seen in parous women aged 40-50, but it can also occur in young, nulliparous women. Coexistence with endometriosis is common.

Diagnosis is suggested by pelvic ultrasound or MRI showing a thickened, heterogeneous junctional zone; histopathology after hysterectomy provides the definitive diagnosis.

Symptoms

Severe dysmenorrhoea

Heavy menstrual bleeding (menorrhagia)

Chronic pelvic pain

Dyspareunia

Symmetrically enlarged, tender uterus

Anaemia from chronic blood loss

Risk Factors

Multiparity

Previous uterine surgery (caesarean, myomectomy, curettage)

Tamoxifen use

Coexisting endometriosis or fibroids

Reproductive age (40-50 years)

Genetic predisposition

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

Severe dysmenorrhoea unresponsive to NSAIDs
Heavy menstrual bleeding causing anaemia
Chronic pelvic pain or dyspareunia
Infertility evaluation

Treatment Methods

NSAIDs and tranexamic acid for symptom control

Combined oral contraceptives or progestin therapy

Levonorgestrel-releasing intrauterine system (Mirena)

GnRH agonists for short-term suppression

Uterine artery embolisation in selected cases

Hysterectomy as definitive therapy when fertility is no longer desired

Which Department to Visit?

You can visit our Kadın Hastalıkları ve Doğum department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Kadın Hastalıkları ve Doğum Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.