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Pure Sensory Neuropathy

Peripheral nerve disease affecting only the sensory nerves.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is Pure Sensory Neuropathy?

Pure sensory neuropathy is a group of diseases that selectively affect the sensory fibers of the peripheral nervous system; motor fibers are largely preserved. Pain, numbness, tingling, and balance disturbance are prominent in patients.

Causes include paraneoplastic syndromes (especially anti-Hu syndrome associated with small cell lung cancer), Sjögren syndrome, vitamin B6 toxicity, HIV, some chemotherapy drugs such as cisplatin, and hereditary neuropathies.

Diagnosis is made with detailed nerve conduction studies, blood tests, autoantibodies, and nerve biopsy when necessary. Treatment is directed at the underlying cause.

Symptoms

Numbness, tingling in hands and feet
Burning-type pain (especially at night)
Balance disturbance and difficulty walking in the dark
Decrease in touch and vibration sensation
Hypersensitivity (allodynia, hyperalgesia)
Muscle strength largely preserved
Frequent falls and loss of dexterity

Risk Factors

Some cancer types (especially small cell lung)
Sjögren syndrome and other autoimmune diseases
Excessive vitamin B6 intake
Some chemotherapy drugs such as cisplatin
HIV and some viral infections
Hereditary sensory neuropathies
Long-term alcohol use

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If progressive numbness or burning pain is present
  • If imbalance and falls have begun
  • If systemic symptoms such as weight loss and weakness accompany
  • New onset in patients with cancer history
  • New symptoms in patients with autoimmune disease diagnosis

Treatment Methods

01
Investigation and treatment of underlying cause
02
Cancer treatment and immunotherapy in paraneoplastic syndromes
03
Immunosuppressive treatments for Sjögren
04
Gabapentin, pregabalin, duloxetine for neuropathic pain
05
Physical therapy and balance training
06
Nutritional support and avoidance of toxic exposure

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.