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Primary Progressive Aphasia

A neurodegenerative syndrome characterized by progressive loss of language functions.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is Primary Progressive Aphasia?

Primary progressive aphasia (PPA) is a neurodegenerative syndrome characterized by slow and progressive impairment of language functions. Other cognitive functions are largely preserved in the first years.

It has three main variants: semantic, agrammatic, and logopenic. It is mainly associated with frontotemporal degeneration and Alzheimer pathologies.

Diagnosis is made with clinical evaluation, neuropsychological tests, and imaging. Speech therapy plays an important role in treatment.

Symptoms

Difficulty finding words
Loss of word meaning
Decreased speech fluency
Impaired sentence structure
Difficulty reading and writing
Slowing of speech rate
Later-added behavioral and cognitive changes

Risk Factors

Familial predisposition
Genetic mutations (GRN, MAPT, C9orf72)
History of frontotemporal degeneration
Alzheimer pathology
Advanced age
History of head trauma
Neurodevelopmental language problems

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If word-finding difficulty is progressive
  • If speech fluency has noticeably decreased
  • If there is difficulty understanding
  • If professional life is affected
  • If there is family history

Treatment Methods

01
Speech and language therapy
02
Cognitive rehabilitation
03
Communication support tools
04
Family and caregiver education
05
Treatment of accompanying behavioral symptoms
06
Genetic counseling

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.