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Posterior Reversible Encephalopathy Syndrome (PRES)

Acute neurological syndrome with vasogenic edema in the parieto-occipital region.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is Posterior Reversible Encephalopathy Syndrome (PRES)?

Posterior reversible encephalopathy syndrome PRES is an acute neurological syndrome characterized by vasogenic edema, especially in the parieto-occipital region.

It is most often associated with hypertensive crisis, eclampsia, immunosuppressive medications, autoimmune diseases and renal failure.

With rapid recognition and treatment of the trigger it is often reversible.

Symptoms

Acute or subacute headache
Generalized tonic-clonic seizures
Visual disturbances: blurred vision, hemianopia, cortical blindness
Confusion and altered consciousness
Focal neurological deficit

Risk Factors

Severe hypertension or hypertensive crisis
Pre-eclampsia, eclampsia and HELLP syndrome
Immunosuppressive medications such as cyclosporine and tacrolimus
Autoimmune diseases such as SLE and vasculitis
Renal failure and chemotherapy

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Sudden severe headache, seizure or visual loss — emergency
  • Hypertensive crisis with neurological symptoms
  • Eclampsia or pre-eclampsia neurological symptoms
  • Acute change in consciousness in immunosuppressive medication use

Treatment Methods

01
Brain MRI with FLAIR sequence to confirm diagnosis
02
Aggressive blood pressure control with intravenous antihypertensive
03
Magnesium sulfate and prompt delivery in eclampsia
04
Discontinuation of triggering immunosuppressive when possible
05
Anti-seizure medication and intensive care follow-up

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.