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Phytotherapy: Silymarin (Milk Thistle) and Liver Health

Silymarin is one of the oldest herbal preparations studied for its hepatocyte-protective effects.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Geleneksel ve Tamamlayıcı Tıp department. Book Appointment →

What is Phytotherapy: Silymarin (Milk Thistle) and Liver Health?

Silymarin is a flavonolignan mixture obtained from the seeds of the Silybum marianum plant. The main component is silibinin.

Hepatocyte membrane stabilization, antioxidant, and antifibrotic effects have been shown in animal and some clinical studies.

The use of IV silibinin in Amanita phalloides poisoning is one of the rare evidence-based supported indications.

Symptoms

Drug hepatotoxicity
Alcohol-related liver disease
NAFLD
Chronic hepatitis
Mushroom poisoning
Bile secretion problems
Mild dyspepsia
Adjuvant hepatoprotective request

Risk Factors

Allergy (Asteraceae family)
Drug interactions (CYP enzymes)
Pregnancy
Pediatric age
Severe coagulopathy
Hormone-sensitive tumors (estrogen-like effect claim)
Pre-operative period

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Physician evaluation in every patient with liver disease
  • Drug interaction control
  • Should not replace standard treatment
  • Efficacy monitoring

Treatment Methods

01
Standard treatment is prioritized
02
Phytotherapy specialist consultation
03
Standard standard dose 420-600 mg silymarin/day
04
IV silibinin is considered in Amanita
05
Liver enzyme monitoring
06
Drug interaction screening
07
Patient consent
08
Side effect monitoring
09
Following evidence development

Which Department to Visit?

You can visit our Geleneksel ve Tamamlayıcı Tıp department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Geleneksel ve Tamamlayıcı Tıp Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.