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Percutaneous Thyroid Fine-Needle Aspiration

Ultrasound-guided cytologic sampling of suspicious thyroid nodules

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Radyoloji department. Book Appointment →

What is Percutaneous Thyroid Fine-Needle Aspiration?

Percutaneous thyroid fine-needle aspiration (FNA) is an ultrasound-guided outpatient procedure in which a thin (22-27 gauge) needle samples cellular material from a thyroid nodule for cytopathologic evaluation. It is the most cost-effective and accurate first-line diagnostic test for differentiating benign from malignant thyroid nodules.

Indications follow ATA, ACR-TIRADS or EU-TIRADS risk stratification, generally requiring sampling of nodules > 1 cm with suspicious features (microcalcifications, irregular margins, taller-than-wide shape, marked hypoechogenicity). Results are reported using the Bethesda System for Reporting Thyroid Cytopathology (categories I-VI), with implied malignancy risk and corresponding management.

Symptoms

Newly discovered thyroid nodule on imaging
Suspicious sonographic features (TIRADS 4-5)
Cervical lymphadenopathy with thyroid nodule
History of head and neck radiation
Family history of thyroid cancer or MEN2
Rapidly growing thyroid mass
Hoarseness with thyroid nodule
Abnormal thyroid scintigraphy

Risk Factors

Severe coagulopathy (relative)
Anticoagulant use (warfarin, DOAC)
Inability to lie still for 15-20 minutes
Severe local skin infection
Cystic nodule with hemorrhagic content
Very small lesions (< 5 mm) limiting accuracy
Severe contrast allergy if needed
Patient anxiety with non-cooperation

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Thyroid nodule found on examination or imaging
  • Family history of thyroid cancer
  • Previous head and neck radiation
  • Hoarseness or dysphagia with thyroid mass
  • Suspicious lymph nodes
  • Rapidly enlarging thyroid mass
  • Abnormal thyroid function with nodule

Treatment Methods

01
Pre-procedural neck ultrasound for nodule risk stratification (TIRADS)
02
Withholding anticoagulants per local protocol
03
Sterile preparation and local anesthetic infiltration
04
Ultrasound-guided needle placement targeting solid hypoechoic regions
05
Capillary aspiration technique with 2-4 passes per nodule
06
On-site cytology adequacy assessment when available
07
Post-procedure 5-10 minute compression for hemostasis
08
Bethesda System cytopathology reporting and follow-up plan
09
Molecular testing (Afirma, ThyroSeq) for indeterminate Bethesda III/IV cases

Which Department to Visit?

You can visit our Radyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Radyoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.