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Ozone Therapy: Inflammatory Bowel Disease

Rectal ozone insufflation and major auto-hemotherapy are used with limited evidence in ulcerative colitis and Crohn's disease.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Geleneksel ve Tamamlayıcı Tıp department. Book Appointment →

What is Ozone Therapy: Inflammatory Bowel Disease?

Ozone therapy is the application of medical ozone (O3) and oxygen mixture in various ways. Major auto-hemotherapy (MAH), minor auto-hemotherapy, rectal insufflation, topical ozonated oil, and ozonated water are common methods.

In IBD studies, rectal ozone insufflation has shown improvement in remission rate, endoscopic score, and quality of life in limited controlled data. Anti-inflammatory, antioxidant, and microbiome modulation mechanisms have been proposed.

Evidence level is low; it does not replace standard immunosuppressive and biological treatment. Appropriate indication, dose, application frequency, and safety profile are not clear. It should be considered only by experienced practitioners with physician approval.

Symptoms

Chronic abdominal pain
Bloody mucous diarrhea
Weight loss
Rectal urgency
Anemia
Perianal disease
Defecation disorders
Treatment-resistant mild-to-moderate IBD

Risk Factors

Ulcerative colitis
Crohn's disease
Active treatment period
Biological treatment
Immunosuppressive treatment
G6PD deficiency
Hemophilia
Pregnancy

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Gastroenterology approval is mandatory
  • Should not be used in active severe disease
  • Biological treatment interaction
  • G6PD screening
  • Does not replace standard treatment
  • Clinical research protocol

Treatment Methods

01
Medical ozone generator
02
Low concentration rectal insufflation
03
Treatment protocol is individualized
04
Short-term application trials
05
Continuation of standard treatment
06
Side effect monitoring
07
G6PD control
08
Gastroenterology collaboration
09
Experienced practitioner

Which Department to Visit?

You can visit our Geleneksel ve Tamamlayıcı Tıp department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Geleneksel ve Tamamlayıcı Tıp Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.