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Multiparametric MRI of the Prostate

PI-RADS-guided imaging for clinically significant prostate cancer.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Radyoloji department. Book Appointment →

What is Multiparametric MRI of the Prostate?

Multiparametric prostate MRI (mpMRI) combines T2-weighted anatomical imaging with diffusion-weighted imaging (DWI) and dynamic contrast-enhanced (DCE) sequences on 3 Tesla scanners with surface or endorectal coils. It is the most accurate non-invasive method for detecting clinically significant prostate cancer.

PI-RADS v2.1 standardizes lesion scoring from 1 (very low) to 5 (very high), guiding the need for targeted biopsy. mpMRI prior to biopsy reduces unnecessary biopsies, increases detection of significant disease and is endorsed by EAU and AUA guidelines.

Symptoms

Elevated PSA without prior biopsy (PSA above 4 ng/mL or age-adjusted threshold)
Continuous PSA rise after negative TRUS biopsy
Active surveillance protocol monitoring
Suspicious DRE finding
Biochemical recurrence after prostatectomy or radiotherapy
Pre-operative staging in confirmed cancer

Risk Factors

Age over 50 (over 45 if positive family history)
African ancestry
BRCA1/2 or HOXB13 germline mutation
Family history of prostate cancer
High dietary fat and processed meat intake
Obesity and metabolic syndrome

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Elevated PSA without prior imaging or biopsy
  • Suspected cancer despite normal initial workup
  • Active surveillance reassessment at 1-2 year intervals
  • Pre-treatment staging in newly diagnosed cancer
  • Suspected local recurrence on rising PSA after definitive therapy

Treatment Methods

01
3 Tesla multiparametric prostate MRI without endorectal coil if possible
02
PI-RADS v2.1 reading by experienced uroradiologist
03
MRI-fusion targeted biopsy for PI-RADS 3-5 lesions
04
MRI-based active surveillance with serial mpMRI
05
Pre-prostatectomy staging including pelvic lymph nodes
06
Post-treatment follow-up MRI for recurrence detection
07
Multidisciplinary tumor board for treatment planning

Which Department to Visit?

You can visit our Radyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.