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MR Spectroscopy (Detailed)

Non-invasive quantification of tissue metabolites for brain, prostate and other tumors.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Radyoloji department. Book Appointment →

What is MR Spectroscopy (Detailed)?

MR spectroscopy (MRS) is a noninvasive MRI-based technique that detects nuclear-magnetic-resonance signals from key tissue metabolites such as N-acetylaspartate (NAA), choline, creatine, lactate, lipids, citrate and myo-inositol.

Single-voxel and chemical-shift imaging acquisitions are tailored to the clinical question. Spectra are interpreted as ratios (Cho/NAA, Cho/Cr) or absolute concentrations.

Applications include brain tumor grading and follow-up, suspected mitochondrial or metabolic disease, hepatic encephalopathy and prostate cancer characterization with multiparametric MRI.

Symptoms

Newly diagnosed brain tumor — characterization and grading
Distinguishing tumor recurrence from radiation necrosis
Suspected mitochondrial or metabolic disorder
Atypical demyelinating disease
Hepatic encephalopathy assessment
Prostate cancer staging in selected cases

Risk Factors

Standard MRI contraindications (devices, severe claustrophobia)
Patient cooperation (motion-sensitive)
Voxel placement near bone or air can degrade spectra
Iron deposition disorders impair signal
Metallic implants in the field of view

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Indeterminate intracranial mass on conventional MRI
  • Post-treatment lesion progression
  • Suspected leukodystrophy or organic acidemia
  • Pediatric developmental regression with imaging needs
  • Equivocal prostate MRI for biopsy targeting

Treatment Methods

01
Multiparametric protocol with conventional and advanced sequences
02
Voxel placement away from skull base and air
03
Quality control with adequate water suppression and shimming
04
Reporting standardized metabolite ratios
05
Multidisciplinary interpretation
06
Clinical correlation with biochemical and pathology data

Which Department to Visit?

You can visit our Radyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.