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MR Perfusion for Brain Tumors

Advanced MRI technique that maps cerebral blood volume to characterize and grade brain tumors.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Radyoloji department. Book Appointment →

What is MR Perfusion for Brain Tumors?

MR perfusion imaging encompasses several techniques (dynamic susceptibility contrast DSC, dynamic contrast enhanced DCE, and arterial spin labeling ASL) that provide quantitative or qualitative maps of microcirculation within the brain.

Cerebral blood volume (CBV) is markedly elevated in high-grade gliomas due to neovascularization, helping to differentiate them from low-grade tumors and non-neoplastic lesions. It is widely used in glioma grading, post-treatment follow-up, and biopsy planning.

Distinguishing tumor recurrence (high CBV) from radiation necrosis (low CBV) is one of the most clinically valuable applications. ASL is particularly useful in pediatric and renal-impaired patients because it does not require gadolinium contrast.

Symptoms

Indications: characterization of newly detected brain mass
Glioma grading and differentiation
Post-treatment evaluation (recurrence vs. necrosis)
Biopsy targeting in heterogeneous tumors
Pre-radiation therapy planning
Lymphoma vs. glioma differentiation
Pediatric brain tumor evaluation

Risk Factors

Pre-existing diagnosis of brain tumor
Post-treatment glioma follow-up
Indeterminate brain lesion on conventional MRI
Pediatric patient (consider ASL)
Renal impairment (avoid gadolinium, use ASL)
Need for non-invasive grading
Suspected tumor recurrence

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • New brain mass requiring characterization
  • Suspected high-grade transformation of low-grade glioma
  • Post-treatment imaging changes (need to distinguish recurrence)
  • Indeterminate enhancing lesion
  • Pediatric brain tumor with treatment planning
  • Lymphoma vs. glioma uncertainty

Treatment Methods

01
Performed in dedicated 1.5T or 3T MRI
02
Bolus gadolinium injection for DSC technique
03
Arterial spin labeling for contrast-free imaging
04
Post-processing with relative CBV and CBF maps
05
Multidisciplinary tumor board interpretation
06
Combined with conventional MRI, MR spectroscopy, and DTI
07
Repeated for treatment response assessment

Which Department to Visit?

You can visit our Radyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.