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Ketogenic Diet and Epilepsy

Classic ketogenic diet is an evidence-based nutritional therapy in the treatment of refractory epilepsy.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Geleneksel ve Tamamlayıcı Tıp department. Book Appointment →

What is Ketogenic Diet and Epilepsy?

Ketogenic diet is a medical nutritional therapy containing high fat, adequate protein, and very low carbohydrates, which directs the body to use ketone bodies as an energy source.

It has been shown in randomized trials to provide a 50% or greater reduction in seizure frequency in pediatric refractory epilepsy. Modified Atkins and low glycemic index diets are more flexible alternatives.

It requires a multidisciplinary team (pediatric neurology, dietitian, nurse). Complications include cardiovascular risk, kidney stones, constipation, and growth retardation.

Symptoms

Refractory pediatric epilepsy
Dravet syndrome
Lennox-Gastaut syndrome
GLUT-1 deficiency
Pyruvate dehydrogenase deficiency
Selected adult epilepsies
Glioma adjuvant studies

Risk Factors

Metabolic contraindications (carnitine deficiency, fatty acid oxidation disorders)
Pancreatitis
Severe liver disease
Porphyria
History of kidney stones
Eating disorder
Compliance difficulty

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Neurology and dietitian supervision is essential
  • Initiation should be done with hospital admission
  • Regular laboratory and growth monitoring is required
  • Cardiovascular profile should be monitored

Treatment Methods

01
Patient selection in multidisciplinary team
02
Metabolic screening and exclusion of contraindications
03
Initiation in hospital admission and ketosis monitoring
04
Ratio adjustment (4:1, 3:1, MCT)
05
Seizure frequency and EEG monitoring
06
Side effect management (citrate, selenium, carnitine)
07
Treatment duration and termination plan

Which Department to Visit?

You can visit our Geleneksel ve Tamamlayıcı Tıp department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Geleneksel ve Tamamlayıcı Tıp Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.