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Hashimoto Encephalopathy

A steroid-responsive encephalopathy associated with thyroid autoantibodies.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is Hashimoto Encephalopathy?

Hashimoto encephalopathy (SREAT — steroid-responsive encephalopathy) is a rare autoimmune encephalopathy that develops in the setting of autoantibody positivity associated with Hashimoto's thyroiditis. Thyroid function is usually normal.

It presents with acute or subacute onset altered consciousness, memory loss, confusion, seizures, tremor, myoclonus, and psychiatric symptoms. Diagnosis is made by thyroid antibody positivity, exclusion of other causes, and rapid response to steroids.

It usually responds dramatically to corticosteroid therapy, so early diagnosis is important.

Symptoms

Clouded consciousness and confusion
Short-term memory loss
Seizures
Myoclonus and tremor
Psychiatric symptoms (hallucination, depression)
Gait disturbances
Headache

Risk Factors

Diagnosis of Hashimoto's thyroiditis
Female sex
Middle age
Other autoimmune diseases
Family history of thyroid disease
Elevated thyroid antibodies
Previous unexplained neurological episodes

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If new neurological symptoms appear in a patient with Hashimoto's diagnosis
  • If unexplained altered consciousness and seizures are present
  • If acute psychiatric symptoms and memory loss occur together
  • If there is rapidly progressive cognitive decline resembling dementia
  • If other causes of encephalitis have been excluded

Treatment Methods

01
High-dose corticosteroids
02
Intravenous immunoglobulin (if unresponsive to steroids)
03
Plasmapheresis (in selected cases)
04
Thyroid function follow-up
05
Seizure control
06
Long-term low-dose steroid maintenance (if needed)

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.