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Frontotemporal Dementia

An early-onset dementia presenting with marked impairment in personality, behavior, and language.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is Frontotemporal Dementia?

Frontotemporal dementia (FTD) is a group of diseases characterized by neurodegenerative atrophy of the frontal and temporal lobes of the brain. It usually begins between ages 45-65, and unlike Alzheimer's disease, personality, behavior, and language are affected at onset rather than memory.

It has three main clinical subtypes: behavioral variant (bvFTD), semantic variant primary progressive aphasia, and non-fluent variant primary progressive aphasia. In the behavioral type, impulse control difficulty, loss of empathy, and socially inappropriate behaviors are prominent.

Familial forms are associated with genetic mutations (C9orf72, MAPT, GRN). Diagnosis is made with clinical, imaging, and sometimes genetic studies.

Symptoms

Personality and behavior changes
Socially inappropriate behaviors and loss of empathy
Impulsivity, compulsive behaviors
Changes in diet and eating habits
Language impairment and word-finding difficulty
Organization and planning problems
Motor findings (in some forms)

Risk Factors

Family history of FTD
Genetic mutations (C9orf72, MAPT, GRN)
History of ALS
History of early-onset dementia
History of head trauma
Advanced age
Metabolic and vascular contributions

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If marked personality change occurs in middle age
  • If problems with social adjustment have developed
  • If language impairment and difficulty with attention have been added
  • If there is family history and suspicion of early onset
  • If daily life is severely affected

Treatment Methods

01
Symptomatic supportive treatment
02
SSRI and atypical antipsychotics (for behavioral findings)
03
Speech and language therapy
04
Family and caregiver education
05
Genetic counseling
06
Counseling on legal and ethical issues

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.