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CT Perfusion for Stroke Evaluation

Rapid CT-based imaging of cerebral blood flow to identify salvageable brain tissue in acute stroke.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Radyoloji department. Book Appointment →

What is CT Perfusion for Stroke Evaluation?

CT perfusion (CTP) involves repeated dynamic scanning during the bolus passage of intravenous contrast, generating maps of cerebral blood flow (CBF), cerebral blood volume (CBV), mean transit time (MTT), and time to peak (Tmax).

In acute stroke, CTP differentiates irreversibly infarcted core (low CBV, low CBF) from reversibly affected penumbra (low CBF, preserved CBV). This is critical for selecting patients for endovascular thrombectomy in the extended time window (6 to 24 hours) per DAWN and DEFUSE 3 criteria.

Modern automated software (e.g., RAPID, Olea) provides rapid quantitative maps that have transformed stroke care. Limitations include radiation dose, contrast use, and motion artifacts.

Symptoms

Acute stroke symptoms (sudden weakness, speech disturbance, vision loss)
Wake-up stroke or unknown onset
Beyond 6-hour window (4.5 to 24 hours)
Need to identify ischemic penumbra
Decision-making for endovascular thrombectomy
Differentiation of stroke mimics
Vasospasm after subarachnoid hemorrhage

Risk Factors

Hypertension
Atrial fibrillation
Diabetes mellitus
Hyperlipidemia
Smoking and obesity
Carotid artery stenosis
Prior stroke or transient ischemic attack

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Sudden onset of focal neurological deficit
  • Suspected stroke beyond 6 hours from onset
  • Wake-up stroke
  • Need for thrombectomy decision-making
  • Suspected stroke mimic
  • Vasospasm assessment in subarachnoid hemorrhage

Treatment Methods

01
Rapid acquisition (less than 5 minutes) in dedicated CT scanner
02
Bolus iodinated contrast through power injector
03
Automated quantitative penumbra and core maps
04
Combined with non-contrast CT and CT angiography
05
Multidisciplinary stroke team review
06
Decision for IV thrombolysis or endovascular thrombectomy
07
Post-treatment imaging follow-up

Which Department to Visit?

You can visit our Radyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Radyoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.