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ADEM (Acute Disseminated Encephalomyelitis)

Usually monophasic demyelinating disease that emerges after infection.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Nöroloji department. Book Appointment →

What is ADEM (Acute Disseminated Encephalomyelitis)?

ADEM is an immune-mediated demyelinating disease that involves the brain and spinal cord in a multifocal manner, usually appearing within days to weeks after a viral infection or vaccination.

It classically follows a monophasic course; however, some cases can proceed with relapses and may convert to MS or MOGAD diagnoses on follow-up.

Encephalopathy (sleepiness, confusion of consciousness) is among the diagnostic criteria and is an important feature distinguishing the disease from MS.

Symptoms

Neurological findings following fever and malaise
Change in consciousness
Headache
Motor weakness
Sensory loss
Gait disorder with ataxia
Seizures

Risk Factors

Recent viral infection
Childhood
Recent vaccination (rarely)
Immune system activation

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Consciousness disorder after viral illness
  • Neurological deficit and fever in a child
  • Development of seizures and weakness
  • Behavioral changes and sleepiness
  • Gait disorder and slurred speech

Treatment Methods

01
High-dose intravenous steroid (methylprednisolone)
02
Immunoglobulin (IVIG)
03
Plasmapheresis in resistant cases
04
Intensive care support
05
Anticonvulsant therapy
06
Rehabilitation program

Which Department to Visit?

You can visit our Nöroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.