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Morphea (Localized Scleroderma)

Localized hardening and thickening of skin patches.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Dermatoloji department. Book Appointment →

What is Morphea (Localized Scleroderma)?

Morphea (localized scleroderma) is a disease characterized by localized fibrosis and sclerosis of skin and underlying tissues. Unlike systemic sclerosis (scleroderma), Raynaud phenomenon is absent, internal organ involvement does not occur and anti-Scl-70 antibody is negative.

Subtypes include plaque (most common), linear (frequent in children — linear sclerosis along the long axis of an extremity), generalized and deep forms. Active lesions show a violet-lilac border ('lilac ring' — a sign of active inflammation).

Most morphea lesions soften spontaneously over 3-5 years; however, linear morphea in children may cause growth asymmetry and contractures. Active and deep forms may require systemic therapy.

Symptoms

Firm, shiny, ivory-colored skin plaque
Violet-lilac border in active lesions (lilac ring)
Skin thickening and reduced mobility
Limb growth asymmetry in linear form (in children)
Joint contractures (in linear form)
Localized alopecia in scalp involvement

Risk Factors

Female sex (2.4-4:1)
Predisposition to autoimmune disease
Trauma (possible trigger in localized lesions)
Borrelia burgdorferi infection (debated association in Europe)

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When firmness or thickening of skin areas is noticed
  • When a violet ring forms around lesions (active disease)
  • When restricted joint movement develops
  • When a child's linear lesion causes growth asymmetry

Treatment Methods

01
Topical corticosteroids and calcineurin inhibitors (in limited plaque form)
02
UVA-1 phototherapy (medium dose — for plaque morphea)
03
Methotrexate plus short-course corticosteroid (in linear and deep forms)
04
Mycophenolate mofetil (for methotrexate intolerance)
05
Physical therapy (contracture prevention — in linear form)

Which Department to Visit?

You can visit our Dermatoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.