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Methamphetamine Use Disorder

A chronic stimulant addiction with severe medical, psychiatric, and social consequences

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Psikiyatri department. Book Appointment →

What is Methamphetamine Use Disorder?

Methamphetamine is a synthetic stimulant that increases dopamine, norepinephrine, and serotonin release. Repeated use produces neuroadaptations that drive intense craving, sleep disturbance, and stimulant-induced psychosis with paranoid delusions and hallucinations.

The disorder follows a pattern of escalating use, social and occupational decline, and risky behaviors including unsafe sex and shared injection equipment. Cardiovascular complications such as accelerated coronary disease, cardiomyopathy, and stroke contribute to early mortality.

Treatment relies on contingency management, cognitive behavioral therapy, and community reinforcement. Off-label trials of mirtazapine, bupropion, and naltrexone have shown modest benefit in subgroups. Care must include attention to dental disease, infectious risks, and co-occurring psychiatric disorders.

Symptoms

Strong craving and tolerance to stimulant effects
Insomnia, weight loss, and dental decay
Paranoia, hallucinations, or violent behavior
Mood swings and depressive crashes after use
Cardiovascular events at unusually young ages

Risk Factors

Family history of substance use disorder
Coexisting attention deficit hyperactivity disorder
History of childhood trauma or conduct problems
Chronic pain or untreated mood disorder
Social environment with stimulant availability

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When cravings or use feel out of control
  • When paranoia or hallucinations develop
  • When chest pain or cardiovascular symptoms arise
  • When suicidal thoughts emerge during withdrawal
  • When pregnancy is planned or confirmed

Treatment Methods

01
Contingency management with reinforcement schedules
02
Cognitive behavioral therapy and motivational interviewing
03
Community reinforcement and twelve-step facilitation
04
Off-label pharmacotherapy in selected cases
05
Treatment of psychosis with antipsychotic medication
06
Cardiovascular and dental medical follow-up
07
Harm reduction with sterile equipment and infection screening

Which Department to Visit?

You can visit our Psikiyatri department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.