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Botulinum Toxin Injection

Botulinum toxin injection — neuromodulator therapy with muscle-relaxing effect applied for medical indications.

An injection method applied by dermatologists and neurologists for the treatment of medical conditions such as excessive sweating, migraine, and certain muscle dystonias.

Indication

  • Hyperhidrosis (excessive sweating of the underarms, palms, or soles)
  • Chronic migraine treatment (with neurology approval)
  • Cervical dystonia (neck muscle spasm)
  • Blepharospasm (involuntary contraction of the eyelid)
  • Jaw muscle pain associated with bruxism (nighttime teeth grinding)
  • Hemifacial spasm (involuntary contraction on one side of the face)

Preparation

  • Discontinuation of blood thinners with physician approval one week before the procedure
  • Absence of active skin infection or acute neurological attack
  • Disclosure of pregnancy or breastfeeding status
  • Sharing of any previous botulinum treatment history

How it's performed

  1. The target area is marked and cleaned with antiseptic
  2. Calculated doses are injected at predetermined points using a fine needle
  3. Application is intradermal for hyperhidrosis and intramuscular for dystonias
  4. The procedure takes 10-20 minutes and generally does not require anesthesia
  5. Topical cooling or ice application may be used for comfort

Post-procedure

  • Avoiding lying down for 4 hours after the procedure
  • Not rubbing the application site within the first 24 hours
  • The effect begins by the end of the first week and reaches full effect in 2-3 weeks
  • Duration of effect is generally 3-6 months; maintenance treatment is given as needed
  • Reporting any adverse effects to the physician

Risks

  • Transient pain, redness, or bruising at the injection site
  • Off-target muscle involvement (e.g., temporary eyelid drooping)
  • Headache or flu-like symptoms (transient)
  • Very rare allergic reactions
  • Effect being shorter or weaker than expected

FAQ

How long does the effect last?

The effect varies by individual but generally lasts 3-6 months. Repeat applications can be planned.

Does it work for excessive sweating?

It is an evidence-based option for the treatment of primary hyperhidrosis. Onset of effect is 3-7 days, and full effect is reached in approximately 2 weeks.

Is it administered during pregnancy?

It is not recommended during pregnancy or breastfeeding.

In which conditions is it contraindicated?

It is not administered in cases of neuromuscular diseases, myasthenia gravis, active infection at the application site, and allergy to toxin components.