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Urethral Carcinoma Treatment

Surgical and oncological management of cancer of the urethra.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Urethral Carcinoma Treatment?

Urethral carcinoma is a rare cancer that arises from the epithelium of the urethra. It is four times more common in women than men. Histological subtypes include squamous cell carcinoma (54%), urothelial carcinoma (34%) and adenocarcinoma (12%).

It most often arises in the bulbar urethra in men and the distal urethra in women. Treatment is selected by location, stage and histology, and organ-sparing surgery may be possible for distal tumours.

Locally advanced and metastatic disease is managed with neoadjuvant chemoradiation and surgery. Prognosis depends on stage and lymph node status; five-year survival in early-stage disease is 50-70%.

Symptoms

Urethral bleeding or bloody discharge
Weak urinary stream or obstruction
Palpable urethral mass or induration
Pelvic or perineal pain
Recurrent urinary tract infections
Urinary retention
Inguinal lymphadenopathy as a sign of metastasis

Risk Factors

HPV infection
History of urethral stricture
Chronic infection and irritation
History of sexually transmitted infection
Lichen sclerosus
Prior radiotherapy

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When urethral bleeding or bloody discharge appears
  • When a palpable mass or induration is felt in the urethra
  • When the urinary stream weakens progressively
  • When inguinal swelling is noticed

Treatment Methods

01
Distal urethrectomy in early-stage distal tumours
02
Anterior pelvic exenteration in advanced female disease
03
Penectomy plus urethrectomy in advanced male disease
04
Inguinal lymph node dissection when nodes are involved
05
Neoadjuvant cisplatin-based chemotherapy
06
Definitive or adjuvant radiotherapy

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Üroloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.