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Ureteral Obstruction Due to Retroperitoneal Fibrosis

A condition in which retroperitoneal fibrosis compresses the ureters and impedes urinary flow.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Ureteral Obstruction Due to Retroperitoneal Fibrosis?

Retroperitoneal fibrosis (RPF) most often forms a fibrous tissue mass in the aortoiliac region, pulling the ureters medially and causing obstruction. This is an important complication followed and treated by urology.

Ureteral involvement may be unilateral or bilateral; it presents with hydronephrosis, flank pain, and deterioration of renal function. It develops as idiopathic (Ormond's disease) or secondary forms.

Urgent management focuses on ureteral drainage; subsequent treatment of the underlying disease (steroids, immunosuppressants, surgical ureterolysis) is then planned.

Symptoms

Flank or back pain
Weakness and weight loss
Nausea and loss of appetite
Decreased urine output
Findings of hydronephrosis
Leg edema
Hypertension

Risk Factors

IgG4-related disease
Ergot derivatives and certain medications
Smoking
Radiotherapy
Autoimmune diseases
Malignancy
Infections

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Unexplained flank pain and hydronephrosis
  • Deterioration of renal function
  • Leg edema and systemic symptoms
  • Follow-up in patients with retroperitoneal fibrosis
  • Suspicion of recurrence after surgery

Treatment Methods

01
Urgent ureteral drainage with DJ stent or percutaneous nephrostomy
02
Steroid therapy (first-line) ± immunosuppressants
03
Retroperitoneal biopsy to exclude malignancy
04
Surgical ureterolysis and intraperitonealization
05
Treatment of the underlying secondary cause
06
Follow-up with renal function and imaging

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.