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Prophylactic Mastectomy

Preventive removal of breast tissue in women at high risk.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Genel Cerrahi department. Book Appointment →

What is Prophylactic Mastectomy?

Prophylactic mastectomy is the surgical removal of breast tissue in women at high risk of breast cancer. It is an option for BRCA1/2 mutation carriers, those with a strong family history, and prior breast cancer patients.

Bilateral risk-reducing mastectomy reduces breast cancer risk by 90-95%. Skin- and nipple-sparing mastectomy is a modern technique that improves cosmetic outcomes with comparable oncological safety.

This decision requires multidisciplinary evaluation. Genetic counseling, psychological support, plastic surgery consultation, and detailed informed consent are critical. Alternatives include close surveillance and chemoprevention.

Symptoms

Presence of BRCA1/2 mutation
Strong family history
Previous breast cancer
Atypical hyperplasia
Lobular carcinoma in situ
History of chest radiotherapy
Li-Fraumeni syndrome

Risk Factors

BRCA1 mutation (55-85% risk)
BRCA2 mutation (45-85% risk)
TP53 mutation
PALB2 mutation
PTEN mutation
Family history
High risk scores

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Detection of a genetic mutation
  • High risk assessment
  • Early breast cancer in the family
  • Stress related to close surveillance
  • Diagnosis of atypical hyperplasia

Treatment Methods

01
Multidisciplinary evaluation
02
Genetic counseling
03
Psychological support
04
Skin-sparing mastectomy
05
Nipple-sparing mastectomy
06
Concurrent implant or autologous reconstruction
07
Long-term follow-up

Which Department to Visit?

You can visit our Genel Cerrahi department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Genel Cerrahi Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.