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Pheochromocytoma Surgery

Surgical removal of catecholamine-secreting tumors of the adrenal medulla.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Genel Cerrahi department. Book Appointment →

What is Pheochromocytoma Surgery?

Pheochromocytoma is a tumor, mostly benign, originating from chromaffin cells of the adrenal medulla and secreting catecholamines (epinephrine, norepinephrine). Extra-adrenal forms are called paragangliomas.

It shows a high rate of genetic transmission (MEN2, VHL, NF1, SDH mutations). Therefore, genetic evaluation is recommended after diagnosis.

Surgery is the only curative treatment; operating without appropriate preoperative medical preparation (alpha blocker, fluid loading, and beta blocker if needed) increases the risk of intraoperative hypertensive crisis.

Symptoms

Paroxysmal hypertension
Headache
Palpitations and tachycardia
Sweating attacks
Anxiety and tremor
Weight loss
Orthostatic hypotension

Risk Factors

MEN2, VHL, NF1 syndromes
SDHB/SDHD mutations
Family history
Previously identified paraganglioma
Detection of incidentaloma
Resistant hypertension at a young age
Recurrent hypertensive crises

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Resistant hypertension and paroxysmal attacks
  • Unexplained headache, palpitations, and sweating
  • Detection of an adrenal mass
  • Need for screening due to family history
  • Suspected recurrence of previous pheochromocytoma

Treatment Methods

01
Preoperative alpha blocker (phenoxybenzamine/doxazosin) for 10-14 days
02
Fluid loading and addition of a beta blocker if needed
03
Laparoscopic adrenalectomy (preferred method)
04
Open surgery for large, invasive, or extra-adrenal tumors
05
Intraoperative blood pressure control
06
Postoperative monitoring for hypoglycemia and hypotension

Which Department to Visit?

You can visit our Genel Cerrahi department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.