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Penectomy (Penile Cancer Surgery)

Partial or total surgical removal of the penis for invasive penile carcinoma.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Penectomy (Penile Cancer Surgery)?

Penectomy is performed for invasive penile squamous cell carcinoma (SCC), the most common penile malignancy, often associated with high-risk HPV (16, 18) infection, phimosis, lichen sclerosus and chronic inflammation. The decision between organ-sparing surgery, partial penectomy and total penectomy depends on tumor location, size, depth of invasion, grade and patient functional priorities.

Surgical principles require adequate negative margins (typically 5-10 mm) to minimize local recurrence. Partial penectomy preserves remnant length sufficient for upright voiding and sexual function when possible, while total penectomy with perineal urethrostomy is performed for proximal or extensive lesions invading the corpora and crura.

Inguinal lymph node management is critical: dynamic sentinel lymph node biopsy or modified inguinal lymphadenectomy is indicated for invasive disease (≥pT1G2). Bilateral pelvic lymphadenectomy is added for ≥2 positive inguinal nodes or extranodal extension. Multidisciplinary care with oncology, reconstructive surgery and psychosexual support is essential.

Symptoms

Persistent penile lesion or ulcer
Phimosis with palpable mass
Bleeding or foul discharge
Inguinal lymphadenopathy
Pain and progressive dysfunction
Inability to retract foreskin
Constitutional symptoms in advanced disease

Risk Factors

High-risk HPV infection (HPV-16, 18)
Phimosis and chronic balanitis
Lichen sclerosus and chronic inflammation
Lack of neonatal circumcision
Smoking
PUVA therapy for psoriasis
Immunosuppression (HIV, transplant)

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Persistent penile lesion >4 weeks
  • Bleeding ulcer or mass
  • Inguinal lymphadenopathy
  • Phimosis with palpable lesion
  • Recurrence after organ-sparing therapy

Treatment Methods

01
Multidisciplinary tumor board evaluation
02
MRI of penis for staging and surgical planning
03
Partial penectomy with 5-10 mm margins
04
Total penectomy with perineal urethrostomy
05
Glansectomy with skin/scrotal flap reconstruction (organ-sparing)
06
Inguinal sentinel node biopsy or modified lymphadenectomy
07
Bilateral pelvic lymphadenectomy when indicated
08
Adjuvant chemotherapy/radiotherapy for high-risk disease
09
Phallic reconstruction (delayed)
10
Psychosexual counseling and rehabilitation

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.