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Neonatal Group B Streptococcal Infection

Newborn infections caused by group B streptococci transmitted during delivery

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Internal Medicine department. Book Appointment →

What is Neonatal Group B Streptococcal Infection?

Group B Streptococcus (Streptococcus agalactiae) colonizes the genital and gastrointestinal tracts and may be transmitted to the newborn during delivery. Early-onset disease occurs within the first week of life, while late-onset disease appears between 7 and 90 days.

Sepsis, meningitis, and pneumonia are the principal clinical syndromes, with high mortality and risk of long-term neurologic sequelae if untreated.

GBS screening during pregnancy (35-37 weeks) and intrapartum antibiotic prophylaxis (penicillin or ampicillin) reduce the incidence of early-onset disease.

Symptoms

Respiratory distress in the newborn
Irritability and feeding difficulty
Fever or hypothermia
Signs of meningitis (bulging fontanelle)
Signs of pneumonia

Risk Factors

Maternal GBS colonization
Preterm delivery
Prolonged rupture of membranes
Intrapartum fever
History of a previous infant with GBS disease

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If the newborn has feeding problems or apnea
  • If fever or hypothermia develops
  • If a seizure or high-pitched cry is observed
  • If a high-risk infant clinically deteriorates

Treatment Methods

01
Empirical ampicillin + gentamicin therapy
02
Switch to penicillin G based on culture results
03
Supportive and intensive care
04
Prolonged therapy if meningitis is present
05
Intrapartum prophylaxis programs
06
GBS screening during pregnancy

Which Department to Visit?

You can visit our Enfeksiyon Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Enfeksiyon Hastalıkları Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.