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Multidisciplinary Treatment of Sarcoma

Coordinated surgical, radiation, and systemic care for soft tissue and bone sarcomas

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Onkoloji department. Book Appointment →

What is Multidisciplinary Treatment of Sarcoma?

Soft tissue and bone sarcomas comprise more than seventy histologic subtypes with very different natural histories and treatment pathways. Diagnostic work-up combines magnetic resonance imaging of the primary tumor, staging chest computed tomography, and image-guided core biopsy reviewed by a sarcoma-specialized pathologist.

Surgery remains the cornerstone for localized disease and aims to remove the tumor with negative margins while preserving function. Neoadjuvant or adjuvant radiotherapy reduces local recurrence risk in extremity and trunk sarcomas, and chemotherapy is selected based on histology, grade, and stage.

Treatment at a high-volume sarcoma center improves outcomes because rare subtypes require specific approaches. Multidisciplinary tumor boards coordinate decisions, and rehabilitation, prosthetics, and survivorship care are essential components of long-term management.

Symptoms

Painless growing soft tissue mass larger than five centimeters
Deep-seated mass beneath fascia
Rapidly enlarging lesion or recurrent mass
Bone pain with night exacerbation
Pathologic fracture in young adult

Risk Factors

Prior radiation therapy years earlier
Genetic syndromes such as Li-Fraumeni or neurofibromatosis
Lymphedema-associated angiosarcoma
Chronic chemical exposure in selected histologies
Familial retinoblastoma with germline RB1 mutation

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When a soft tissue mass exceeds five centimeters
  • When a deep mass grows quickly
  • When bone pain persists at night or rest
  • When biopsy is needed to confirm sarcoma
  • When tertiary referral is sought for treatment

Treatment Methods

01
Image-guided core biopsy at a sarcoma center
02
Wide local excision with limb salvage when possible
03
Neoadjuvant or adjuvant radiotherapy
04
Histology-directed chemotherapy regimens
05
Rehabilitation and prosthetic services
06
Long-term surveillance imaging
07
Multidisciplinary tumor board coordination

Which Department to Visit?

You can visit our Onkoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.