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Mirizzi Syndrome

Obstructive jaundice caused by external compression of the common bile duct by a large stone in the gallbladder neck or cystic duct.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Genel Cerrahi department. Book Appointment →

What is Mirizzi Syndrome?

Mirizzi syndrome is the obstruction of the adjacent common bile duct (choledochus) by compression or inflammation from a stone impacted in the gallbladder neck or cystic duct.

It is staged according to the Csendes classification from type 1 (pure compression) to type 5 (cholecystobiliary fistula ± enteric fistula). Treatment plan is determined according to this stage.

It has a higher coexistence with gallbladder cancer; ruling out malignancy at diagnosis is important. MR cholangiography and ERCP are the cornerstone of diagnosis and planning.

Symptoms

Jaundice (obstructive type)
Right upper quadrant pain
Dark urine, pale stool
Pruritus
Fever (if cholangitis is added)
Loss of appetite and weight loss
Nausea and vomiting

Risk Factors

Long-term symptomatic gallstone disease
Large stone in the gallbladder neck
Chronic cholecystitis
Advanced age
Female gender
Previous cholangitis attacks
Coexistence with gallbladder cancer

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Newly developing painless or painful jaundice
  • Development of jaundice in a known gallstone patient
  • Pruritus and weight loss
  • Recurrent cholangitis attacks
  • Need for surgical evaluation after suspicious ERCP findings

Treatment Methods

01
MRCP and ERCP for detailed anatomical evaluation
02
Laparoscopic or open cholecystectomy in type 1 (careful dissection)
03
Partial cholecystectomy + bile duct repair (T-tube or primary) in type 2 fistula
04
Biliodigestive anastomosis (choledochoduodenostomy, hepaticojejunostomy) in advanced types
05
Preoperative endoscopic stent decompression
06
Frozen biopsy and oncologic resection planning when malignancy is suspected

Which Department to Visit?

You can visit our Genel Cerrahi department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.