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Mallory-Weiss Syndrome

Esophageal mucosal tear caused by severe vomiting.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Genel Cerrahi department. Book Appointment →

What is Mallory-Weiss Syndrome?

Mallory-Weiss syndrome is upper gastrointestinal bleeding characterized by a longitudinal tear involving the mucosa and submucosa at the gastroesophageal junction following severe vomiting, retching, or coughing.

The syndrome was first described by Mallory and Weiss in 1929. The main causes include alcohol abuse, hyperemesis gravidarum, bulimia, severe coughing, and endoscopic trauma. It is responsible for approximately 5-15% of upper GI bleeding.

In most cases bleeding stops spontaneously, but some patients require endoscopic or surgical intervention. Endoscopy is the gold standard for both diagnosis and treatment. The prognosis is generally good.

Symptoms

Bloody vomiting after severe vomiting
Coffee-ground vomiting
Black tarry stool
Epigastric pain
Weakness and dizziness
Tachycardia
Findings of anemia

Risk Factors

Alcohol use
Hyperemesis gravidarum
Bulimia nervosa
Severe coughing fits
Hiatal hernia
NSAID use
Coagulation disorders

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Blood after vomiting
  • Coffee-ground emesis
  • Black melena-like stool
  • Dizziness and syncope
  • Severe epigastric pain

Treatment Methods

01
Hemodynamic stabilization
02
IV fluids and blood product support
03
Proton pump inhibitors
04
Endoscopic hemostatic treatment
05
Epinephrine injection
06
Thermal coagulation or clip placement
07
Surgery in rare cases

Which Department to Visit?

You can visit our Genel Cerrahi department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.