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Kaposi Sarcoma (Skin)

An HHV-8-related vascular tumor presenting as purple-red nodules on the skin.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Dermatoloji department. Book Appointment →

What is Kaposi Sarcoma (Skin)?

Kaposi sarcoma is a tumor of endothelial cell origin triggered by HHV-8 (Kaposi sarcoma-associated herpesvirus). Four clinical forms are described: classic, endemic, iatrogenic (with immunosuppressive therapy), and AIDS-associated.

Skin lesions present as purple-red patches, plaques, or nodules. They are seen especially on the lower extremities, face, and oral mucosa. Lymph node, lung, and gastrointestinal involvement may occur.

Treatment is planned according to the form, extent, and the patient's immune status. Antiretroviral therapy is the cornerstone in HIV-positive patients.

Symptoms

Purple-red skin patches and plaques
Firm, raised purple nodules
Oral lesions (especially on the palate)
Edema in the lower extremities
Lymph node enlargement
Cough, dyspnea, abdominal pain in visceral involvement
Fatigue and weight loss (in disseminated cases)

Risk Factors

HHV-8 infection
HIV/AIDS
Immunosuppression after organ transplantation
Mediterranean and Central African origin
Older male age
Immune system weakening
Same-sex relations and HIV risk

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When new purple-red patches are noticed on the skin
  • When purple lesions are seen in the mouth
  • When dyspnea, cough, hemoptysis develop
  • When weight loss and chronic diarrhea accompany
  • When new skin lesions appear in a known HIV patient

Treatment Methods

01
Antiretroviral therapy in HIV-positive patients
02
Reduction of immunosuppression
03
Local treatments (cryotherapy, intralesional chemotherapy, radiotherapy)
04
Systemic chemotherapy (pegylated liposomal doxorubicin, paclitaxel)
05
Immunotherapy and targeted therapies
06
Regular oncologic follow-up

Which Department to Visit?

You can visit our Dermatoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Dermatoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.