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D2/D3 Gastrectomy and Lymph Node Dissection

Radical oncological surgery for gastric cancer with extended lymphadenectomy.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Genel Cerrahi department. Book Appointment →

What is D2/D3 Gastrectomy and Lymph Node Dissection?

D2 gastrectomy is the standard oncological technique for gastric cancer in which, in addition to perigastric lymph nodes, the celiac trunk, left gastric, common hepatic, splenic artery and hepatoduodenal ligament lymph nodes (N2) are removed.

D3 dissection extends to paraaortic lymph nodes (16a2/b1) and is performed in selected advanced cases. Techniques pioneered in Japan are now accepted as standard practice in Western centres.

D2 lymphadenectomy significantly improves 5-year survival and reduces local recurrence in gastric cancer. In experienced centres, mortality of D2 gastrectomy has fallen to 2-3%.

Symptoms

Resectable gastric adenocarcinoma
T2-T4 stage gastric cancer
Clinically node-positive disease
Proximal, mid and distal gastric tumours
Signet ring cell carcinoma
Resectable cases without dissemination
Good performance status
Resectability after neoadjuvant therapy

Risk Factors

Pancreatic fistula (5-10%)
Splenic vein thrombosis
Anastomotic (oesophagojejunal) leak
Duodenal stump dehiscence
Massive haemorrhage
Prolonged operative time
Malnutrition and advanced age
Postoperative weight loss

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Fever and abdominal pain
  • Enteric or biliary fluid in drains
  • Early satiety and vomiting
  • Fresh bleeding or melaena
  • Dysphagia (anastomotic stricture)
  • Excessive weight loss

Treatment Methods

01
Preoperative staging (PET-CT, endoscopic ultrasound)
02
Neoadjuvant chemotherapy (FLOT regimen)
03
Decision between total or subtotal gastrectomy
04
D2 lymphadenectomy (stations No. 1-12)
05
Spleen-preserving splenic hilar dissection
06
Roux-en-Y oesophagojejunostomy reconstruction
07
Feeding jejunostomy (in selected cases)
08
Early postoperative enteral nutrition

Which Department to Visit?

You can visit our Genel Cerrahi department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Genel Cerrahi Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.