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Cutaneous Sarcoidosis

A disease with non-caseating granulomas in the skin in systemic sarcoidosis or in isolated form.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Dermatoloji department. Book Appointment →

What is Cutaneous Sarcoidosis?

Cutaneous sarcoidosis is the dermatological reflection of systemic sarcoidosis, in which non-caseating epithelioid granulomas form in the skin. About 25 percent of patients have cutaneous involvement, and it is sometimes the first sign of systemic disease.

Its clinical spectrum is very wide: macules, papules, plaques, nodules, alopecia, lupus pernio, erythema nodosum, sarcoidosis on scars and hypopigmented lesions are different presentations. It is called the 'great imitator'.

Multidisciplinary evaluation is required to exclude systemic involvement of sarcoidosis in the lungs, eyes, joints, liver and heart. Treatment is planned according to lesion severity and the presence of systemic involvement.

Symptoms

Purple-blue lupus pernio plaques on the nose and cheeks
Erythematous small papules on the face
Sarcoidal reactions within scars and tattoos
Hypopigmented or maculopapular rash
Subcutaneous nodules (Darier-Roussy)
Erythema nodosum (acute Löfgren's syndrome)
Persistent plaques and skin atrophy

Risk Factors

Family history of sarcoidosis
Specific HLA types
African ancestry (especially aggressive course)
Environmental dust and mineral exposure
Infectious triggers
Female sex (some subtypes)

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When persistent purple-blue plaques are present on the face
  • If new nodules develop within old scars or tattoos
  • If shortness of breath accompanies skin lesions
  • If extensive erythema nodosum develops
  • If unexplained joint pain accompanies

Treatment Methods

01
Topical and intralesional corticosteroid
02
Systemic corticosteroid (in severe cases)
03
Hydroxychloroquine and methotrexate
04
TNF-alpha inhibitors (infliximab, adalimumab)
05
Minocycline and doxycycline (mild cases)
06
Multidisciplinary follow-up of systemic involvement

Which Department to Visit?

You can visit our Dermatoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.