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Buccal Mucosa Graft Urethroplasty

Reconstructive urethral surgery using a graft of buccal (cheek) mucosa to reconstruct urethral strictures of bulbar, penile, or panurethral location, providing high success rates and durable patency in long, complex strictures unsuitable for primary anastomotic repair.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

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This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Üroloji department. Book Appointment →

What is Buccal Mucosa Graft Urethroplasty?

Buccal mucosa graft urethroplasty is a microsurgical urethral reconstruction technique in which a free graft of buccal mucosa is harvested from the cheek and used to widen or replace strictured segments of the male urethra, restoring physiologic caliber and durable patency in strictures too long for primary excision and anastomosis.

Buccal mucosa is the preferred graft material because it is non-keratinized, elastic, easy to harvest, has rich submucosal vascular bed for revascularization, lacks hair, and resists urinary contact, providing superior long-term outcomes compared with skin grafts.

Surgical techniques include dorsal onlay (Barbagli), ventral onlay (McAninch), lateral onlay, and augmented anastomotic urethroplasty, selected based on stricture location, length, prior surgery, and surgeon experience; both single-stage and two-stage repairs are possible.

Symptoms

Long-segment urethral stricture (greater than 2–3 cm) of bulbar, penile, or panurethral location
Recurrent stricture after dilation, urethrotomy, or previous urethroplasty
Urethral stricture from lichen sclerosus (balanitis xerotica obliterans), failed hypospadias repair, or radiation
Symptoms of obstruction: weak stream, straining, prolonged voiding, urinary retention, recurrent urinary tract infection
Postoperative donor-site discomfort: oral pain, transient salivary gland obstruction, mouth tightness
Postoperative urethral fistula, diverticulum, restenosis, or graft contracture in selected cases

Risk Factors

Long stricture length (greater than 2 cm), pan-urethral involvement, multiple prior interventions
Lichen sclerosus involving urethra and glans, with chronic inflammation impairing graft take
Smoking, diabetes, peripheral vascular disease, and prior radiation impairing wound healing
Inadequate buccal mucosa harvest with damage to Stensen's duct or oral structures
Poor surgical technique with inadequate graft fixation, hematoma, or inadequate spongioplasty
Patient nonadherence to postoperative voiding instructions and follow-up cystoscopy

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Patient with recurrent obstructive voiding symptoms after dilation or urethrotomy — referral to reconstructive urologist for definitive urethroplasty assessment
  • Lichen sclerosus or hypospadias-related stricture — early referral to subspecialty center for staged or single-stage repair
  • Postoperative new urinary leak, infection, or worsening stream — urgent urologic review
  • Persistent oral pain, salivary obstruction, or trismus after graft harvest — oral and maxillofacial review
  • Long-term follow-up: annual uroflowmetry and selective cystoscopy to detect early recurrence

Treatment Methods

01
Preoperative evaluation: retrograde urethrogram, voiding cystourethrogram, cystoscopy, ultrasound urethrography, and assessment of stricture etiology, length, and location
02
Perioral preparation, harvest of buccal mucosa graft from cheek (avoiding Stensen's duct), defatting, and shaping to required length and width
03
Surgical exposure of strictured urethral segment with stricturotomy, placement of graft as dorsal, ventral, or lateral onlay, fixation to corpus spongiosum or tunica albuginea, and tension-free urethral closure
04
Postoperative urethral catheterization for 2–3 weeks, voiding cystourethrogram before catheter removal, and patient education about voiding mechanics
05
Long-term surveillance with uroflowmetry, post-void residual, and cystoscopy at scheduled intervals to detect and manage stricture recurrence early

Which Department to Visit?

You can visit our Üroloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.