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Biologic Therapy for Uveitis

Control of chronic uveitis with anti-TNF and immunosuppressive agents

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Göz Hastalıkları department. Book Appointment →

What is Biologic Therapy for Uveitis?

Uveitis is intraocular inflammation that can lead to vision loss through its complications. Beyond corticosteroids, immunosuppressives (methotrexate, mycophenolate, ciclosporin) and biologic agents are used.

Anti-TNF-alpha therapy (adalimumab, infliximab) is particularly effective in Behcet disease, HLA-B27 associated uveitis and uveitis linked to juvenile idiopathic arthritis.

Intravitreal dexamethasone implant, fluocinolone implant and anti-VEGF therapy are also used in selected cases.

Symptoms

Redness and light sensitivity
Blurred vision
Floaters
Eye pain
Decreased visual acuity
Associated systemic disease

Risk Factors

HLA-B27 associated disease
Behcet disease
Sarcoidosis
Juvenile idiopathic arthritis
Inflammatory bowel disease
Multiple sclerosis

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • If ocular redness fails to respond to treatment
  • If blurred vision develops
  • If pain and photophobia are present
  • If episodes are recurrent
  • If additional systemic symptoms appear

Treatment Methods

01
Slit-lamp examination and OCT
02
Systemic workup (HLA, infection screening)
03
Topical and systemic corticosteroids
04
Immunosuppressive therapy
05
Anti-TNF biologic agents
06
Intravitreal implants

Which Department to Visit?

You can visit our Göz Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Göz Hastalıkları Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.