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Apheresis Procedures in Hematology

Therapeutic blood component separation for plasma, cells, and stem cell collection

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Hematoloji department. Book Appointment →

What is Apheresis Procedures in Hematology?

Apheresis is an extracorporeal procedure that uses a cell separator to remove a specific blood component from the patient and return the remainder. It includes therapeutic plasma exchange, red cell exchange, leukapheresis, plateletpheresis, and stem cell collection.

In hematology, apheresis is used to treat thrombotic thrombocytopenic purpura, severe hemolytic anemias, hyperleukocytosis in acute leukemias, sickle cell vaso-occlusive crises, and to collect autologous or allogeneic hematopoietic stem cells for transplantation.

Procedures are performed in dedicated apheresis units with central or large peripheral venous access, anticoagulation with citrate, and continuous monitoring for hypocalcemia, volume shifts, and bleeding.

Symptoms

Need for central venous catheter in some patients
Tingling or muscle cramps from citrate
Transient hypotension or hypocalcemia
Multiple sessions over days or weeks
Coordinated with chemotherapy, transfusion, or transplantation

Risk Factors

Thrombotic thrombocytopenic purpura and atypical HUS
Hyperleukocytosis in acute leukemias
Sickle cell crises with stroke or acute chest
Patients planned for stem cell transplantation
Severe drug-induced or autoimmune cytopenias

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When emergency therapeutic apheresis is indicated
  • When stem cell collection is planned
  • When citrate or anticoagulation reactions occur
  • Before vascular access placement
  • When catheter complications develop

Treatment Methods

01
Therapeutic plasma exchange for TTP and other indications
02
Red cell exchange for sickle cell crises
03
Leukapheresis for hyperleukocytosis
04
Plateletpheresis for symptomatic thrombocytosis
05
Autologous and allogeneic stem cell collection
06
Citrate management and calcium replacement
07
Vascular access care and complication management

Which Department to Visit?

You can visit our Hematoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Hematoloji Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.