Allergen Immunotherapy for Allergic Rhinitis

Disease-modifying treatment that desensitizes the immune system to specific aeroallergens.

Written by: Saygı Hospital Health Guide Editorial Board

Published: February 1, 2026

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our KBB (Kulak Burun Boğaz) department. Book Appointment →

What is Allergen Immunotherapy for Allergic Rhinitis?

Allergen immunotherapy involves the repeated administration of standardized allergen extracts to induce immunologic tolerance and reduce symptoms of allergic rhinitis and rhinoconjunctivitis.

It is delivered as subcutaneous immunotherapy with periodic injections or as sublingual immunotherapy using drops or tablets, typically over three to five years.

Properly indicated, it can decrease symptom and medication scores, prevent progression to asthma in some patients and provide long-term benefit after the course is completed.

Symptoms

Persistent rhinorrhea

Sneezing paroxysms

Nasal itching and congestion

Itchy and watery eyes

Postnasal drip

Sleep disturbance from nasal obstruction

Frequent need for antihistamines

Risk Factors

Confirmed IgE sensitization to relevant aeroallergens

Inadequate response to pharmacotherapy

Coexisting allergic asthma

Significant impact on quality of life

Long pollen exposure season

Occupational allergen exposure

Family history of atopy

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

Symptoms not controlled by intranasal steroids and antihistamines
Coexisting uncontrolled asthma
Severe local or systemic reaction during therapy
New onset wheezing
Pregnancy planning during therapy
Plan for surgery or new biologic therapy
Need for re-evaluation of allergen panel

Treatment Methods

Detailed history and skin or specific IgE testing

Selection of subcutaneous or sublingual route based on patient profile

Build-up phase with gradually increasing doses

Maintenance phase for three to five years

Concomitant pharmacotherapy as needed

Strict observation after subcutaneous injections

Periodic reassessment of efficacy and safety

Which Department to Visit?

You can visit our KBB (Kulak Burun Boğaz) department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About KBB (Kulak Burun Boğaz) Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.