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Small Cell Lung Cancer

Aggressive, chemotherapy-sensitive form of lung cancer

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Göğüs Hastalıkları department. Book Appointment →

What is Small Cell Lung Cancer?

Small cell lung cancer (SCLC) is an aggressive neuroendocrine-origin tumor accounting for approximately 15% of all lung cancers. Its association with smoking is exceptionally strong, and it shows a marked tendency for early metastasis.

It is classified as limited-stage (single hemithorax plus regional lymph nodes) and extensive-stage disease. SCLC is highly chemosensitive but responses are typically transient. Adding immunotherapy has improved overall survival in extensive-stage disease.

Symptoms

Rapidly progressive cough and dyspnea
Hemoptysis
Superior vena cava syndrome
Paraneoplastic syndromes (SIADH, Cushing)
Rapid weight loss

Risk Factors

Heavy smoking (>30 pack-years)
Asbestos exposure
Radon gas exposure
Family history of lung cancer

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Rapidly progressive respiratory symptoms
  • Signs of SVC syndrome (facial edema, neck venous distention)
  • Findings suggesting paraneoplastic syndromes

Treatment Methods

01
Limited-stage: etoposide + cisplatin with concurrent thoracic radiotherapy
02
Extensive-stage: chemotherapy plus immunotherapy (atezolizumab or durvalumab)
03
Prophylactic cranial irradiation after complete response
04
Second-line: topotecan or lurbinectedin
05
Radiotherapy for brain metastasis
06
Supportive care and palliative measures

Which Department to Visit?

You can visit our Göğüs Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Göğüs Hastalıkları Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.