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Pulmonary Lymphangitic Carcinomatosis

A condition resulting from the spread of malignant tumor cells to the lung lymphatics.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Göğüs Hastalıkları department. Book Appointment →

What is Pulmonary Lymphangitic Carcinomatosis?

Pulmonary lymphangitic carcinomatosis is a condition that develops when an extrapulmonary or pulmonary primary malignancy spreads to the lung lymphatic channels. Breast, lung, gastric, pancreatic, and prostate cancers are the most common causes.

Accumulation of tumor cells in the lymphatics disrupts lymphatic flow and leads to interstitial edema, fibrosis, and the development of pulmonary hypertension. This process causes rapidly progressive dyspnea.

The diagnosis is supported by high-resolution CT; intralobular septal thickening and a nodular pattern are characteristic. Definitive diagnosis is made by lung biopsy. Treatment is directed at the underlying malignancy.

Symptoms

Rapidly progressive dyspnea
Dry cough
Fatigue
Weight loss
Chest pain
Hypoxia
Findings of underlying cancer

Risk Factors

Breast cancer
Lung adenocarcinoma
Gastric cancer
Pancreatic cancer
Prostate cancer
Thyroid cancer
Cervical cancer

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Rapidly progressing dyspnea in a known cancer patient
  • Unexplained dry cough
  • Weight loss and fatigue
  • Development of hypoxia

Treatment Methods

01
Chemotherapy of the underlying malignancy
02
Systemic steroid therapy
03
Diuretics
04
Oxygen support
05
Palliative care
06
Dyspnea control with opioids

Which Department to Visit?

You can visit our Göğüs Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Göğüs Hastalıkları Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.