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Prevention of Hyperoxia-Induced Lung Injury

Protecting the lung from injury with high FiO2

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Göğüs Hastalıkları department. Book Appointment →

What is Prevention of Hyperoxia-Induced Lung Injury?

Treatment with FiO2 >60% for longer than 24-48 hours carries a risk of lung injury. In COPD, the SpO2 target is 88-92%, while in other acute conditions the target is 94-98%.

Specific situations such as bleomycin chemotherapy require even tighter limitation of FiO2 (<30%). Hyperoxia can cause substernal pain, cough, atelectasis, and an ARDS-like picture.

Symptoms

Substernal pain
Cough
Atelectasis
ARDS-like picture

Risk Factors

Prolonged high FiO2
Bleomycin history
COPD
Newborn

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Worsening despite oxygen therapy
  • Need for controlled oxygen in COPD

Treatment Methods

01
SpO2 target monitoring
02
FiO2 minimization
03
PEEP optimization
04
FiO2 <30% with bleomycin
05
High FiO2 limited to <48 hours
06
SpO2 88-92% target in COPD

Which Department to Visit?

You can visit our Göğüs Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Göğüs Hastalıkları Department

Let us help you

You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.