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Diffuse Alveolar Hemorrhage

Widespread intra-alveolar bleeding of the lungs originating from the pulmonary microcirculation.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Göğüs Hastalıkları department. Book Appointment →

What is Diffuse Alveolar Hemorrhage?

Diffuse alveolar hemorrhage (DAH) is a syndrome characterized by bleeding from the capillaries and small vessels in the pulmonary microcirculation into the alveoli. Vasculitides, Goodpasture's syndrome, connective tissue diseases, drugs, and coagulopathies are the most common causes.

Clinically, hemoptysis, anemia, hypoxemia, and diffuse infiltrations on radiology are seen. However, hemoptysis may not occur in approximately one-third of patients. Progressively bloody fluid in sequential BAL lavages is diagnostic.

Early diagnosis and identification of the cause are essential. Treatment varies depending on the underlying cause; high-dose steroids and immunosuppressive therapy are used in immune-mediated causes.

Symptoms

Hemoptysis (may or may not be present)
Dyspnea
Cough
Fever
Hypoxia
Fatigue
Findings of anemia

Risk Factors

ANCA-associated vasculitis
Anti-GBM disease
Systemic lupus erythematosus
Antiphospholipid syndrome
Bone marrow transplantation
Drug use (propylthiouracil, cocaine)
Coagulopathy and anticoagulant use

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Hemoptysis with shortness of breath
  • Sudden onset of anemia and hypoxia
  • New findings in patients with autoimmune disease
  • Unexplained lung infiltrations

Treatment Methods

01
Treatment of the underlying cause
02
High-dose corticosteroids
03
Immunosuppressive therapy
04
Plasmapheresis (in immune-mediated causes)
05
Oxygen and mechanical ventilation
06
Correction of coagulation disorder

Which Department to Visit?

You can visit our Göğüs Hastalıkları department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

Learn About Göğüs Hastalıkları Department

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.