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Takotsubo Cardiomyopathy Detail

Detailed evaluation of stress-induced reversible LV apical ballooning.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Takotsubo Cardiomyopathy Detail?

Takotsubo cardiomyopathy (TC) or stress cardiomyopathy is a transient left ventricular dysfunction triggered by emotional or physical stress. It mimics acute myocardial infarction with electrocardiographic and biomarker changes but coronary angiography is normal.

It is most commonly seen in postmenopausal women (>90%). Apical ballooning, mid-ventricular and reverse takotsubo morphologies are described. Catecholamine surge-induced microvascular dysfunction and direct myocardial toxicity are pathophysiological mechanisms.

Symptoms

Acute chest pain (acute coronary syndrome-like)
Dyspnoea
Syncope
Cardiogenic shock (in severe cases)
Ventricular arrhythmias
Heart failure findings

Risk Factors

Postmenopausal female (>50 years)
Severe emotional stress (loss of loved one, financial crisis)
Acute medical illness (sepsis, surgery)
Catecholamine excess (pheochromocytoma)
Neurological events (subarachnoid haemorrhage, stroke)
Hyperthyroidism

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Acute chest pain + ST elevation - emergency
  • Cardiogenic shock + ACS suspicion
  • After severe emotional/physical stress new dyspnoea
  • Cardiac arrest survivor evaluation
  • Recurrent TC suspicion

Treatment Methods

01
ECG (ST elevation, T inversion)
02
Cardiac enzymes (mild troponin elevation)
03
Coronary angiography (normal coronaries — diagnostic)
04
Echocardiography (apical akinesia/ballooning)
05
Cardiac MR (LGE absence — distinguishes from MI)
06
Beta-blocker (long-term prevention)
07
ACEi/ARB (during recovery period)
08
Inotropic support (in cardiogenic shock — avoid catecholamines)
09
Mechanical circulatory support (Impella/ECMO — refractory cases)
10
Treatment of complications (LVOT obstruction, mural thrombus)
11
Recurrence risk warning (5-10%)

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.