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Reperfusion Strategies in Acute MI

Primary PCI and fibrinolytic therapy in ST-elevation myocardial infarction.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Reperfusion Strategies in Acute MI?

Early reperfusion therapy (restoration of coronary blood flow) is life-saving in ST-elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention (PCI) is the preferred method, and door-to-balloon time should be kept below 90 minutes.

If PCI cannot be delivered within 120 minutes, fibrinolytic therapy is administered. Tenecteplase, alteplase and reteplase are commonly used fibrinolytic agents. Rescue or routine angiography is planned 2-24 hours after fibrinolysis.

Symptoms

Severe chest pain (>20 min, unresponsive to nitroglycerin)
Radiation to the left arm, jaw or back
Cold sweating and pallor
Nausea and vomiting
Dyspnoea
ST-segment elevation on ECG

Risk Factors

Smoking
Hypertension and diabetes
Hyperlipidaemia
Family history of premature CAD
Obesity and sedentary lifestyle
Stress

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Chest pain lasting more than 20 minutes — call 112 (EMERGENCY)
  • Chest pain with cold sweating and pallor
  • When ST elevation is detected on ECG
  • New chest pain in a patient with known coronary disease

Treatment Methods

01
Primary PCI (door-to-balloon <90 min — gold standard)
02
Fibrinolytic therapy (when PCI access >120 min)
03
Aspirin + P2Y12 inhibitor (ticagrelor or prasugrel)
04
Anticoagulant (heparin)
05
Early initiation of beta-blocker and statin
06
Cardiac rehabilitation (after discharge)

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.