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Patent Ductus Arteriosus (PDA)

Failure of the fetal ductus arteriosus to close after birth.

Written by: Saygı Hospital Health Guide Editorial Board
Published:

This content is for general information; please consult your physician for diagnosis and treatment.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Patent Ductus Arteriosus (PDA)?

Patent ductus arteriosus is failure of the fetal bridge between the aorta and the pulmonary artery, which normally closes within the first days of life. In term infants it usually closes within 48 hours.

A persistent duct creates continuous shunting from the aorta to the pulmonary artery. Small PDAs are often asymptomatic, while large PDAs cause pulmonary overcirculation, left heart overload, and a risk of endocarditis.

Premature infants frequently respond to medical therapy; in term infants and adults, catheter or surgical closure is preferred. Large untreated PDAs can progress to Eisenmenger physiology.

Symptoms

Feeding difficulty and tiring quickly in infants
A continuous 'machinery' murmur at the left sternal border and infraclavicular region
Hyperdynamic, bounding pulses
Wide pulse pressure
Recurrent respiratory infections
Exertional dyspnea and palpitations
Cyanosis in large defects (particularly in the feet)

Risk Factors

Prematurity and low birth weight
Rubella infection during pregnancy
Birth at high altitude
Family history of PDA
Female sex
Down syndrome and other genetic conditions
Birth asphyxia and hypoxia

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • When a continuous murmur is detected in the newborn
  • Worsening respiratory distress in a premature infant
  • Easy fatigability and feeding difficulty in a child
  • In known PDA patients, for febrile illness or cardiac symptoms

Treatment Methods

01
Medical closure with ibuprofen, indomethacin, or paracetamol in prematures
02
Catheter closure with a coil or device
03
Surgical ligation (in unsuitable anatomy)
04
Heart failure therapy: diuretics and fluid restriction
05
Evaluation for endocarditis prophylaxis
06
Long-term cardiology follow-up after the procedure

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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You can make an appointment with our specialists or contact us for your concerns.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.