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Myocardial Perfusion Scintigraphy Detail

Detection of coronary ischaemia with SPECT/PET nuclear cardiology imaging.

Written by: Saygı Hospital Health Guide Editorial Board
Last updated:

This content has been compiled by the Saygı Hospital Health Guide Editorial Board and is periodically reviewed by a specialist physician.

References (5)

This content is for informational purposes only and does not constitute medical advice. You can book an appointment at our Kardiyoloji department. Book Appointment →

What is Myocardial Perfusion Scintigraphy Detail?

Myocardial perfusion scintigraphy (MPS) is a nuclear cardiology imaging method used to evaluate coronary artery disease. With SPECT (Tc99m-sestamibi/tetrofosmin) or PET (Rb-82/N-13 ammonia) imaging, regional myocardial perfusion is detected at rest and stress.

Stress is induced by exercise (treadmill/bicycle) or pharmacological agents (regadenoson, dipyridamole, dobutamine). PET MPS provides higher resolution, quantitative myocardial blood flow (MBF) and myocardial flow reserve (MFR) measurements compared to SPECT.

Symptoms

Stable angina pectoris
Atypical chest pain
Pre-operative cardiac risk assessment (intermediate-high risk)
Myocardial viability assessment (Hibernating myocardium)
Stress test indeterminate after CAG
Functional significance assessment in known CAD

Risk Factors

Coronary artery disease (multivessel)
Diabetic CAD (silent ischaemia)
Microvascular disease (Cardiac Syndrome X)
Vasospastic angina
Cardiac amyloidosis (PYP scintigraphy)
Sarcoidosis (FDG-PET)

When to See a Doctor?

If you experience any of the following symptoms, seek medical attention promptly:

  • Anatomic-functional discordance after CAG
  • Pre-operative cardiac risk stratification
  • Hibernating myocardium suspicion
  • Microvascular ischaemia investigation
  • Functional assessment after revascularisation

Treatment Methods

01
Tc99m-sestamibi SPECT (1- or 2-day protocol)
02
Rb-82 PET (rapid same-day stress-rest protocol)
03
Pharmacological stress (regadenoson preferred)
04
Gated SPECT (LV function + perfusion)
05
Quantitative MBF/MFR (PET — microvascular function)
06
Reversible defect (ischaemia)
07
Fixed defect (scar)
08
Multidisciplinary CAD management plan
09
Patient counselling (radiation dose 8-15 mSv)
10
Insulin/hypoglycaemia management in diabetic patients

Which Department to Visit?

You can visit our Kardiyoloji department for these complaints. Our specialist physicians will create the most suitable treatment plan for you.

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Health Disclaimer: The information on this page is prepared for general informational purposes only. It does not replace medical diagnosis and treatment. Please consult your physician for your complaints. Saygı Hospital does not accept responsibility for actions taken based on the information on this page.